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VOL. 2, ISSUE 1 (2026)
Impact of chrononutrition on insulin sensitivity and glycemic control: A systematic review
Authors
Roja H R, Aparag Paul, Souvik Tewari
Abstract
Chrononutrition, the
study of the interaction between meal timing and circadian rhythms, has emerged
as a critical determinant of metabolic health. This systematic review evaluates
the impact of chrononutrition on insulin sensitivity and glycemic control. A
structured search of electronic databases (PubMed, Scopus, Web of Science, and
Google Scholar) was conducted to identify relevant studies published between
2010 and 2025. Evidence from observational studies, randomized controlled
trials, and systematic reviews indicates that meal timing, frequency, and
alignment with circadian rhythms significantly influence glucose metabolism.
Early-day eating, time-restricted feeding (TRF), and consistent meal patterns
are associated with improved insulin sensitivity and glycemic outcomes, whereas
late-night eating, breakfast skipping, and circadian misalignment contribute to
impaired glucose tolerance and increased insulin resistance. However,
heterogeneity in study design and population characteristics limits definitive
conclusions. Chrononutrition represents a promising adjunct strategy for
metabolic disease prevention and management, but further high-quality
longitudinal studies are needed.
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Pages:11-16
How to cite this article:
Roja H R, Aparag Paul, Souvik Tewari "Impact of chrononutrition on insulin sensitivity and glycemic control: A systematic review". World Journal of Current Research, Vol 2, Issue 1, 2026, Pages 11-16
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